The period of pregnancy is
a very important aspect of fetal growth and development. Maternal weight gain
during pregnancy is associated with fetal macrosomia. Generally, delays in low
maternal weight gain have been linked to limitations in fetal growth and
development, and there is some evidence that low maternal weight gain is
associated with an increased risk of pre-term delivery. Objective: To determine
the effect of hyperlipidaemia during pregnancy on neonatal growth and birth
weight. Methodology: This was a prospective cross sectional study on pregnant
who delivered between (1-6) weeks and non pregnant women as a control. Result:
There was significant difference between TG of the exposed group (0.87 ± 0.29) mmol/L
versus the controls (0.75 ± 0.31) mmol/L p = 0.04. T.CHOL was also significant between the exposed (4.45 ± 0.75) mmol/L
and controls (4.03 ± 1.04) mmol/L p =
0.029. Comparing LDL-C of both groups was (2.71 ± 0.79) mmol/L for the cases
and (2.26 ± 0.75) mmol/L for the controls a p = 0.005. Also there was a significant difference between HDL-C of the exposed
(1.28 ± 0.33) mmol/L and controls (1.45 ± 0.44) mmol/L p = 0.044. There was no correlation between baby’s weight and
maternal BMI, p = 0.950. Postnatal
lipids did not also show relationship with baby’s weight. Dyslipidaemia during
the postpartum period did not reflect a subsequent increase in birth weight. Conclusion:
Generally, the
study demonstrated strongly that BMI does not affect birth weight especially in women who are
overweight and obese. More so, dyslipidaemia during the postpartum period (1-6)
weeks did not correlate or reflect a subsequent increase in birth weight and a
possible obesity in later life.
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