A new dolabrane dinorditerpene, tagalsine X(1), was isolated from the
leaves of Ceriops tagal, along with
five known analogues (2-6). Their structures were established on the basis of
spectroscopic data or comparison with the literatural data. Their cytotoxic
activities against four human carcinoma cell lines (CNE-2, HCT-116, HepG2and A549)
were also evaluated, which displayed that only compound 2 had significant
cytotoxicity against those cell lines with IC50 values of 13.57, 42.32, 11.21
and 15.23 μM, respectively.
Cite this paper
Wu, X. , Liao, H. , Lu, H. and Zhang, C. (2016). A New Dolabrane Dinorditerpene from Ceriops tagal. Open Access Library Journal, 3, e2957. doi: http://dx.doi.org/10.4236/oalib.1102957.
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