All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99


Long Term Follow-Up of ABO Incompatible Kidney Transplantation—A Study from India

DOI: 10.4236/oalib.1102544, PP. 1-5

Subject Areas: Nephrology

Keywords: ABO Incompatible Kidney Transplantation, India, Long Term

Full-Text   Cite this paper   Add to My Lib


Background: There is a need to do ABO incompatible kidney transplantation in a country like India where deceased donor transplantation is not common. More than 90% transplantations are done with living donors. Although short term results have been reported from 4 centers, there is paucity of data on long term follow-up of such patients. Methods: The data of 18 patients who had undergone ABO incompatible transplantation exceeding a follow-up of 12 months up to 66 months were analyzed. It was compared with the data of compatible kidney transplantation during the same period. Results: In both the groups, there was a similar incidence of urinary tract infection and gastroenteritis with complete recovery. Tuberculosis was successfully treated in 2 patients who had undergone ABO incompatible transplantation. The graft function was excellent with an average follow-up period of 38.2 months. There was no patient mortality during the follow-up period. Conclusion: The long term outcome of ABO incompatible kidney transplantation is similar to compatible kidney transplantation despite the increased incidence of short term complications.

Cite this paper

Ravichandran, R. and Kannan, S. (2016). Long Term Follow-Up of ABO Incompatible Kidney Transplantation—A Study from India. Open Access Library Journal, 3, e2544. doi:


[1]  Wilpert, J., Fischer, K., Pisarski, P., Wiech, T., Daskalakis, M., Ziegler, A., Neumann-Haefelin, E., Drognitz, O., Emmerich, F., Walz, G. and Geyer, M. (2010) Long-Term Outcome of ABO-Incompatible Living Donor Kidney Transplantation Based on Antigen-Specific Desensitization. An Observational Comparative Analysis. Nephrology Dialysis Transplantation, 25, 3778-3786.
[2]  Montgomery, J., Berger, J., Warren, D., James, N., Montgomery, R. and Segev, D. (2012) Outcomes of ABO-Incom- patible Kidney Transplantation in the United States. Transplantation, 1.
[3]  Uchida, J., Kuwabara, N., Machida, Y., Iwai, T., Naganuma, T., Kumada, N. and Nakatani, T. (2012) Excellent Outcomes of ABO-Incompatible Kidney Transplantation: A Single-Center Experience. Transplantation Proceedings, 44, 204-209.
[4]  Oettl, T., Halter, J., Bachmann, A., Guerke, L., Infanti, L., Oertli, D., Mihatsch, M., Gratwohl, A., Steiger, J. and Dickenmann, M. (2008) ABO Blood Group-Incompatible Living Donor Kidney Transplantation: A Prospective, Single-Centre Analysis Including Serial Protocol Biopsies. Nephrology Dialysis Transplantation, 24, 298-303.
[5]  Lipshutz, G. (2011) ABO Blood Type—Incompatible Kidney Transplantation and Access to Organs. Archives of Surgery, 146, 453.
[6]  Tanabe, K. (2007) Japanese Experience of ABO-Incompatible Living Kidney Transplantation. Transplantation, 84, S4-S7.
[7]  Bhadauria, D., Goel, A., Kaul, A., Sharma, R., Gupta, A., Ruhela, V., Gupta, A., Vardhan, H. and Prasad, N. (2015) Cryptosporidium Infection after Renal Transplantation in an Endemic Area. Transplant Infectious Disease, 17, 48-55.
[8]  John, G., Shankar, V., Abraham, A., Mukundan, U., Thomas, P. and Jacob, C. (2001) Risk Factors for Post-Transplant Tuberculosis. Kidney International, 60, 1148-1153.
[9]  Iqbal, T., Naqvi, R. and Akhter, S.F. (2010) Frequency of Urinary Tract Infection in Renal Transplant Recipients and Effect on Graft Function. Journal of Pakistan Medical Association, 60, 826-829.
[10]  Shin, M. and Kim, S. (2011) ABO Incompatible Kidney Transplantation—Current Status and Uncertainties. Journal of Transplantation, 2011, 1-11.
[11]  Habicht, A., Broker, V., Blume, C., Lorenzen, J., Schiffer, M., Richter, N., Klempnauer, J., Haller, H., Lehner, F. and Schwarz, A. (2011) Increase of Infectious Complications in ABO-Incompatible Kidney Transplant Recipients—A Single Centre Experience. Nephrology Dialysis Transplantation, 26, 4124-4131.
[12]  Ravichandran, R., Kanakaraj, A., Shakthivel, A. and Srinivas, C. (2012) ABO Incompatible Kidney Transplantation— A Single Center Experience. Indian Journal of Transplantation, 6, 103-106.
[13]  Virani, Z., Bhagat, A., Rajput, P., Shah, B., Pagar, S., Bala, S. and Dawane, V. (2014) Our Initial Experience with ABO-Incompatible Transplant. Indian Journal of Transplantation, 8, 132-133.
[14]  Jha, P.K., Bansal, S.B., Sethi, S.K., et al. (2015) ABO-Incompatible Renal Transplantation in Developing World— Crossing the Immunological (and Mental) Barrier. Indian Journal of Nephrology, 26, 113-118.
[15]  Jha, V. (2013) Current Status of End-Stage Renal Disease Care in India and Pakistan. Kidney International Supplements, 3, 157-160.
[16]  Tobian, A., Shirey, R., Montgomery, R., Cai, W., Haas, M., Ness, P. and King, K. (2010) ABO Antibody Titer and Risk of Antibody-Mediated Rejection in ABO-Incompatible Renal Transplantation. American Journal of Transplantation, 10, 1247-1253.


comments powered by Disqus

Contact Us


微信:OALib Journal