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Primary Extranodal Non-Hodgkin’s Lymphoma Mimicking a Painful Gingival Swelling: A Case Report

DOI: 10.4236/oalib.1102363, PP. 1-7

Subject Areas: Dentistry, Surgery & Surgical Specialties, Oncology, Hematology

Keywords: Mandible, Diffuse Large B Cell Lymphoma, Non-Hodgkin’s Lymphoma, Periapical Lesion, Oral Cancer

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Abstract

Diffuse large B cell lymphoma (DLBCL), the most common subtype of non-Hodgkin’s lymphoma (NHL), is an aggressive, rapidly growing neoplasm which is the most common lymphoid neoplasm affecting adults. Jaw involvement of NHL is rare, but among jaw lesions, the maxilla is more frequently involved than the mandible. Primary lymphoma of the mandible is often misdiagnosed clinically. A 43-year-old man admitted to the Ege University, Department of Oral and Maxillofacial Surgery at the Faculty of Dentistry with one month complaint of gingival pain and swelling in the left side of mandibular premolar area. Biopsy was planned and was done to send for histopathological examination. Histopathology by using immunohistochemistry techniques confirmed a diagnosis of a diffuse large B-cell lymphoma. In conclusion, dentists and oral maxillofacial surgeons who encounter patients with a suspicious oral lesion inconsistent with the presenting head/neck/face complaint, must include malignancy as part of their differential diagnosis.

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Tetik, A. , Peskersoy, C. , Koyuncu, B. O. , Solmaz, M. C. and Saydam, G. (2016). Primary Extranodal Non-Hodgkin’s Lymphoma Mimicking a Painful Gingival Swelling: A Case Report. Open Access Library Journal, 3, e2363. doi: http://dx.doi.org/10.4236/oalib.1102363.

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