Diffuse large B cell lymphoma (DLBCL), the most
common subtype of non-Hodgkin’s lymphoma (NHL), is an aggressive, rapidly
growing neoplasm which is the most common lymphoid neoplasm affecting adults.
Jaw involvement of NHL is rare, but among jaw lesions, the maxilla is more
frequently involved than the mandible. Primary lymphoma of the mandible is
often misdiagnosed clinically. A 43-year-old man admitted to the Ege
University, Department of Oral and Maxillofacial Surgery at the Faculty of
Dentistry with one month complaint of gingival pain and swelling in the left
side of mandibular premolar area. Biopsy was planned and was done to send for
histopathological examination. Histopathology by using immunohistochemistry
techniques confirmed a diagnosis of a diffuse large B-cell lymphoma. In
conclusion, dentists and oral maxillofacial surgeons who encounter patients
with a suspicious oral lesion inconsistent with the presenting head/neck/face
complaint, must include malignancy as part of their differential diagnosis.
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