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In Vitro Anthelmintic Activity of Mucuna pruriens (DC) and Canarium schweinfurthii (Engl) on Ascaris suum

DOI: 10.4236/oalib.1101102, PP. 1-8

Subject Areas: Pharmacology, Organic Chemistry

Keywords: Anthelmintic Activity, Mucuna pruriens, Canarium schweinfurthii, Pheretima posthuma, A. suum, Eclodibility

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The in vitro anthelmintic evaluation of the crude extracts and solvent partitions on Pheretima posthuma and Ascarissuum (eggs and L2 stage) respectively showed significant results at the same concentration (10, 20, 40 and 80 mg/ml). This study provides a clear evidence for usage of Mucuna pruriens and Canarium schweinfurthii as an anthelmintic. The most potent ovicidal partition of C. schweinfurthii (Engl) leaves and bark and leaves of M. pruriens (DC) is hexane (100.00 ± 0.33), chloroform (98.20 ± 0.12) and chloroform (98.70 ± 0.88) partitioned crude respectively at 80 mg/ml while the most potent larvicidal partition is hexane (0.06%), chloroform (0.1%) and chloroform (0.2%). The active compounds are predominantly in the non-polar solvent which supports the tegumental diffusing activity of the compounds.

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Okoli, B. J. , Ayo, R. G. , Habila, J. D. , Japhet, S. L. and Ndukwe, G. I. (2015). In Vitro Anthelmintic Activity of Mucuna pruriens (DC) and Canarium schweinfurthii (Engl) on Ascaris suum. Open Access Library Journal, 2, e1102. doi:


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