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Mar 08, 2019Open    AccessArticle

Anti-Tumor Effect and Mechanism of Parthenolide in Gastric Cancer Cellline BGC-823

Wenhao Zhu, Hanni Zhang, Yunliang Guo, Keli Ge, Yonghong Zhou
Objective: To study the anti-tumor effect and mechanism of parthenolide in gastric cancer cell BGC-823. Methods: The cck8 assay was used to detect the changes of BGC-823 cells viability after treatment with different con-centrations of parthenolide at different time points. The proliferation ability of BGC-823 cells was detected by clone formation assay. And the cell cycle and apoptosis were measured by flow cy

Sep 26, 2018Open    AccessArticle

Mucinous Breast Carcinoma: Anatomo-Clinical Radiological and Therapeutic Features

Asma Korbi, Houda Mhabrech, Ennaceur Farouk, Ons Cherif, Amira Daldoul, Chiraz Hafsa, Ahmed Hajji, Raja Faleh
Introduction: Mucinous carcinoma of the breast constitutes 1% to 4% of all breast cancers. Two different forms of presentation are distinguished: pure mucinous carcinoma and mixed mucinous carcinoma. The purpose of our work was to clarify the anatomo-clinical and radiological particularities of this rare form of breast cancer. Materials and methods: This was a retrospective study of a series of 14 cases of mucinous carcinoma of th

Jan 11, 2018Open    AccessArticle

Papillary Carcinoma Arising in Thyroglossal Duct Cyst: A Retrospective Analysis (Cancer of the Thyroid or Primary Cancer of the Thyroglossal Cyst)

Paolo Gamba, Umberto Pignatelli, Giampiero D’Addazio, Gabriella Licursi, Luca Gentile, Ugo Moz
Thyroglossal duct cysts are one of the most common congenital abnormalities of the cervical region. Complications of these swellings are rare, and among these, appearance of a carcinoma has also been noted. Thyroglossal duct cyst carcinoma (TGDC) is a rare entity and its management is controversial. The incidence of thyroid papillary carcinoma in thyroglossal duct cyst is less than 1%, in most cases, the diagnosis is made postoper

Dec 22, 2017Open    AccessArticle

A Rare Collision Tumor: Tracheal Sarcomatoid Carcinoma Invading a Papillary Thyroid Carcinoma

Mofiyinfolu Sokoya, Carissa M. Thomas, Marcia Eustaquio
A collision tumor involving a tracheal sarcomatoid carcinoma and a papillary thyroid carcinoma has never been reported in the literature. A 78-year-old female presented with a large neck mass and hoarseness. A fine needle aspiration demonstrated papillary thyroid carcinoma. Imaging revealed a right thyroid mass invading into the tracheal lumen with bulky ipsilateral lymphadenopathy. The patient underwent a total thyroidectomy, tra

Dec 01, 2017Open    AccessArticle

Primary Neuroendocrine Carcinoma of the Breast: A Case Report and Review of the Literature

H. Bhiri, S. Zaied, H. Mhabrech, I. Abbes, O. Zoukar, H. Bargaoui, A. Korbi, R. Falah, A. Ben Salem, M. Njima, H. Laajili, A. Daldoul
Primary neuroendocrine carcinoma of the breast is a rare tumor that has been considered special features within conventional breast carcinomas until recently. In this article, we present a case report of a 77-year-old woman with a metastatic grade I primary neuroendocrine carcinoma of the breast that has been growing for seven years. The patient was treated with hormone therapy with good outcome.

Nov 30, 2017Open    AccessArticle

Laparoscopic Abdominoperineal Resection for Low Rectal Cancer at National Cancer Hospital of Vietnam

Binh V. Pham, Anh T. Pham, Su Bin Kim, Tran Van Thuan, Nguyen Tien Quang
Introduction: Results of laparoscopic colectomies from developing nations are reported rarely. We report our results of laparoscopic abdominoperineal resec-tion (LAPR) for low rectal cancer at K Hospital (National Cancer Hospital of Vietnam). Materials & Methods: From January 2012 to December 2015, a to-tal of 135 patients who were diagnosed with low rectal adenocarcinoma were recruited to evaluate for LAPR surgical outcome perfor

Oct 20, 2017Open    AccessArticle

EGFR Mutation Status and TKI Therapy in Patients with Advanced Vulvar Cancer: Clinical Observations

Kun Liu, Yong Yang, Cunde Wang, Yufeng Wang, Ying Zhu
Vulvar cancer is a rare female genital neoplasm representing 5% of all gynecological malignancies, and occurring most frequently in women between the ages of 65 and 75. The most common histological type is squamous cell carcinoma followed by melanoma, basal cell carcinoma, and adenocarcinoma. In the early disease stage, surgical treatment can be effective; however, once recurrence and metastas

Oct 18, 2017Open    AccessArticle

Therapeutic Specificities and Prognosis of Advanced Stage and Metastatic Bladder Cancers in a Tunisian University Hospital

Zaied Sonia, Khechine Wiem, Bourigua Rim, Abbess Ibtissem, Ktari Kamel, Ben Ali Yosri, Daldoul Amira
In Tunisia, bladder cancer represents the first urological cancer before even prostate cancer. However, its diagnosis is often delayed to the stage of invasive tumor. Systemic chemotherapy represents an option for inoperable and/or metastatic forms. Our study’s aims were to report our center’s therapeutic results for locally advanced and metastatic forms of bladder cancer and to analyze its prognosis factors. In our 40 patients wi

Jul 18, 2017Open    AccessArticle

Male Breast Cancer: Case Studies and Literature Review

Zaied Sonia, Khechine Wiem, Abbess Ibtissem, Amina Ben Salem, Aloui Salma, Bargaoui Hayfa, Zoukar Olfa, Mhabrech Houda, Faleh Raja, Laajili Hayet, Daldoul Amira
Male breast cancer is a rare disease. In Tunisia, it represents 1% of all breast cancers and 1.6% of Male neoplasia. This work is a retrospective study about 5 male patients with breast cancer, treated in the department of medical oncology at Fattouma Bourguiba University Hospital of Monastir (Tunisia) during a period of 3 years from March 2013 to March 2016. Results showed that: invasive ductual carcinoma was the histological typ

Jul 06, 2017Open    AccessArticle

Abrikossoff’s Tumor of the Vulva, Case Report and Literature Review

Hayet Laajili, Sonia Zaidi, Imen Bannour, Olfa Zoukar, Khawla Massoudi, Asma Korbi, Raja Faleh
Abrikossoff’s tumor or granular cell tumor is a rare soft and usually benign tissue neoplasm of neural origin. It occurs usually in the neck region or in the head. About 16% occur in the vulva. Some malignant cases have been reported in literature. Granular cell tumor was described first by Abrikossoff in 1926. The histogenesis of granular cell tumors is unknown. The clinical diagnosis of vulv