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Jan 11, 2018Open    AccessArticle

Papillary Carcinoma Arising in Thyroglossal Duct Cyst: A Retrospective Analysis (Cancer of the Thyroid or Primary Cancer of the Thyroglossal Cyst)

Paolo Gamba, Umberto Pignatelli, Giampiero D’Addazio, Gabriella Licursi, Luca Gentile, Ugo Moz
Thyroglossal duct cysts are one of the most common congenital abnormalities of the cervical region. Complications of these swellings are rare, and among these, appearance of a carcinoma has also been noted. Thyroglossal duct cyst carcinoma (TGDC) is a rare entity and its management is controversial. The incidence of thyroid papillary carcinoma in thyroglossal duct cyst is less than 1%, in most cases, the diagnosis is made postoper

Dec 22, 2017Open    AccessArticle

A Rare Collision Tumor: Tracheal Sarcomatoid Carcinoma Invading a Papillary Thyroid Carcinoma

Mofiyinfolu Sokoya, Carissa M. Thomas, Marcia Eustaquio
A collision tumor involving a tracheal sarcomatoid carcinoma and a papillary thyroid carcinoma has never been reported in the literature. A 78-year-old female presented with a large neck mass and hoarseness. A fine needle aspiration demonstrated papillary thyroid carcinoma. Imaging revealed a right thyroid mass invading into the tracheal lumen with bulky ipsilateral lymphadenopathy. The patient underwent a total thyroidectomy, tra

Dec 01, 2017Open    AccessArticle

Primary Neuroendocrine Carcinoma of the Breast: A Case Report and Review of the Literature

H. Bhiri, S. Zaied, H. Mhabrech, I. Abbes, O. Zoukar, H. Bargaoui, A. Korbi, R. Falah, A. Ben Salem, M. Njima, H. Laajili, A. Daldoul
Primary neuroendocrine carcinoma of the breast is a rare tumor that has been considered special features within conventional breast carcinomas until recently. In this article, we present a case report of a 77-year-old woman with a metastatic grade I primary neuroendocrine carcinoma of the breast that has been growing for seven years. The patient was treated with hormone therapy with good outcome.

Nov 30, 2017Open    AccessArticle

Laparoscopic Abdominoperineal Resection for Low Rectal Cancer at National Cancer Hospital of Vietnam

Binh V. Pham, Anh T. Pham, Su Bin Kim, Tran Van Thuan, Nguyen Tien Quang
Introduction: Results of laparoscopic colectomies from developing nations are reported rarely. We report our results of laparoscopic abdominoperineal resec-tion (LAPR) for low rectal cancer at K Hospital (National Cancer Hospital of Vietnam). Materials & Methods: From January 2012 to December 2015, a to-tal of 135 patients who were diagnosed with low rectal adenocarcinoma were recruited to evaluate for LAPR surgical outcome perfor

Oct 20, 2017Open    AccessArticle

EGFR Mutation Status and TKI Therapy in Patients with Advanced Vulvar Cancer: Clinical Observations

Kun Liu, Yong Yang, Cunde Wang, Yufeng Wang, Ying Zhu
Vulvar cancer is a rare female genital neoplasm representing 5% of all gynecological malignancies, and occurring most frequently in women between the ages of 65 and 75. The most common histological type is squamous cell carcinoma followed by melanoma, basal cell carcinoma, and adenocarcinoma. In the early disease stage, surgical treatment can be effective; however, once recurrence and metastas

Oct 18, 2017Open    AccessArticle

Therapeutic Specificities and Prognosis of Advanced Stage and Metastatic Bladder Cancers in a Tunisian University Hospital

Zaied Sonia, Khechine Wiem, Bourigua Rim, Abbess Ibtissem, Ktari Kamel, Ben Ali Yosri, Daldoul Amira
In Tunisia, bladder cancer represents the first urological cancer before even prostate cancer. However, its diagnosis is often delayed to the stage of invasive tumor. Systemic chemotherapy represents an option for inoperable and/or metastatic forms. Our study’s aims were to report our center’s therapeutic results for locally advanced and metastatic forms of bladder cancer and to analyze its prognosis factors. In our 40 patients wi

Jul 18, 2017Open    AccessArticle

Male Breast Cancer: Case Studies and Literature Review

Zaied Sonia, Khechine Wiem, Abbess Ibtissem, Amina Ben Salem, Aloui Salma, Bargaoui Hayfa, Zoukar Olfa, Mhabrech Houda, Faleh Raja, Laajili Hayet, Daldoul Amira
Male breast cancer is a rare disease. In Tunisia, it represents 1% of all breast cancers and 1.6% of Male neoplasia. This work is a retrospective study about 5 male patients with breast cancer, treated in the department of medical oncology at Fattouma Bourguiba University Hospital of Monastir (Tunisia) during a period of 3 years from March 2013 to March 2016. Results showed that: invasive ductual carcinoma was the histological typ

Jul 06, 2017Open    AccessArticle

Abrikossoff’s Tumor of the Vulva, Case Report and Literature Review

Hayet Laajili, Sonia Zaidi, Imen Bannour, Olfa Zoukar, Khawla Massoudi, Asma Korbi, Raja Faleh
Abrikossoff’s tumor or granular cell tumor is a rare soft and usually benign tissue neoplasm of neural origin. It occurs usually in the neck region or in the head. About 16% occur in the vulva. Some malignant cases have been reported in literature. Granular cell tumor was described first by Abrikossoff in 1926. The histogenesis of granular cell tumors is unknown. The clinical diagnosis of vulv

May 18, 2017Open    AccessArticle

Secretory Breast Carcinoma, a Case Report and Literature Review

Hayet Laajili, Amina Ben Salem, Sonia Zaidi, Imen Bannour, Khouloud Marzouk, Asma Korbi, Raja Faleh
Secretory breast carcinoma (SBC) is a very rare subtype of breast carcinoma that reported mostly in young women, with a median age of 25 years. Despite the low frequency, SBC elicits pathologic interest because of their unique morphology and excellent prognosis. Authors report a 23-year-old woman presented with a nodule in retro areolar region of her right breast. Microbiopsic examination reve

Apr 19, 2017Open    AccessArticle

Neuron Specific Enolase, a Biomarker of Breast Cancer Cerebral Metastasis

Cristina Dumitrescu, Lieveke Ameye, Sofia Latifyan, Ziad Elali, Dominique Lossignol
Introduction: The diagnosis of brain metastasis and/or epilepsy remains a challenge in neurological symptomatic and asymptomatic cancer patients. Despite improved imagery and clinical approach, an early diagnosis requires more tools. Neuron Specific Enolase (NSE) is a specific molecular marker for mature nerve cells dosed at high levels in fetal and early postnatal brain, and is also a tumor marker in some types of neuroendocrine