Jul 31, 2020Open AccessArticle
Advancements in technology such as proteomics, genomics have led to the concept of personalized medicine wherein the integration of biomarkers into clinic directs cancer therapeutics. Traditional staging has a stochastic element which can only predict the outcome without actual consideration of intrapatient heterogeneity. In this review, we will look at the biomarkers that prove to be valuable tools for the personalization of cancer therapeutics among lung and breast cancer patients.
Apr 20, 2020Open AccessArticle
Rhabdomyosarcomas (RMS) is one of the most common sarcomas in children but rare in adults. It can occur in any anatomic location but most often presents in the head and neck region. Herewith, we report a rare case of primary orbito-ethmoidal rhabdomyosarcoma in a 29-year-old female. The patient underwent induction chemotherapy and achieved surprising results.
Jan 08, 2020Open AccessArticle
Breast cancer (BC) is the second incidence and the fifth leading cause to cancer death in the worldwide. In developing countries, the number of BC cases is still increased annually accompanied with the changes of lifestyle and screening programs. Nevertheless, the majority of BC patients are diagnosed as non-curative stage. Thereby, systemic therapy always plays an important role in BC treatment strategies. Among chemotherapy regi
Aug 15, 2019Open AccessArticle
Introduction: Colorectal cancer (CRC) is a major public health problem in Morocco. Knowledge of risk factors is the first step in raising awareness. The objective of this work was to evaluate the knowledge of health professionals working at the Mohammed VI center for the treatment of cancers on risk factors of colorectal cancer. Patients and methods: We conducted a cross-sectional, descriptive, exhaustive study of the hospital per
Mar 22, 2019Open AccessArticle
Objective: To observe the therapeutic effect of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil and Oteracil Potassium in the treatment of locally advanced esophageal cancer. Method: The patients with locally advanced esophageal cancer admitted to our hospital were randomly divided into observation group and control group. The control group was treated with three-dimensional conformal radiotherapy alone; t
Mar 08, 2019Open AccessArticle
Objective: To study the anti-tumor effect and mechanism of parthenolide in gastric cancer cell BGC-823. Methods: The cck8 assay was used to detect the changes of BGC-823 cells viability after treatment with different con-centrations of parthenolide at different time points. The proliferation ability of BGC-823 cells was detected by clone formation assay. And the cell cycle and apoptosis were measured by flow cy
Sep 26, 2018Open AccessArticle
Introduction: Mucinous carcinoma of the breast constitutes 1% to 4% of all breast cancers. Two different forms of
presentation are distinguished: pure mucinous carcinoma and mixed mucinous carcinoma. The purpose of our work was to clarify the anatomo-clinical and radiological particularities of this rare form of breast cancer. Materials and
methods: This was a retrospective study of a series of 14 cases of mucinous carcinoma of th
Jan 11, 2018Open AccessArticle
Thyroglossal duct cysts
are one of the most common congenital abnormalities of the cervical region.
Complications of these swellings are rare, and among these, appearance of a
carcinoma has also been noted. Thyroglossal duct cyst carcinoma (TGDC) is a
rare entity and its management is controversial. The incidence of thyroid
papillary carcinoma in thyroglossal duct cyst is less than 1%, in most cases, the diagnosis is made postoper
Dec 22, 2017Open AccessArticle
A collision tumor involving a tracheal sarcomatoid carcinoma
and a papillary thyroid carcinoma has never been reported in the literature. A 78-year-old
female presented with a large neck mass and hoarseness. A fine needle aspiration
demonstrated papillary thyroid carcinoma. Imaging revealed a right thyroid mass
invading into the tracheal lumen with bulky ipsilateral lymphadenopathy. The patient underwent
a total thyroidectomy, tra
Dec 01, 2017Open AccessArticle
Primary neuroendocrine carcinoma of the breast is a rare tumor that has been considered special features within conventional breast carcinomas until recently. In this article, we present a case report of a 77-year-old woman with a metastatic grade I primary neuroendocrine carcinoma of the breast that has been growing for seven years. The patient was treated with hormone therapy with good outcome.