Jan 16, 2019Open AccessArticle
Objectives: The aims and objectives of this systematic review are to inves-tigate the different theories underlining major depression and suicide while exploring the correlation between BDNF, major depression and suicide. Method: Literature was researched through the University of Malta research platform and statistical reports published by the Maltese National Statistics Office, Eurostat and World Health Org
Feb 27, 2018Open AccessArticle
Protein Tyrosine Phosphatase 1B (PTP1B) plays a key
role in down-regulation of insulin and leptin signaling pathways. Therefore,
development of novel inhibitors of PTP1B has becoming research focus in reducing blood sugar levels for Diabetes
Mellitus and Obesity. Hence, we selected two isomer Selaginellins (1 and 2) to
explain and analyze the
binding mechanism of the two potential inhibitors against the PTP1B by molecule
Nov 13, 2015Open AccessArticle
In this article we are going to introduce certain applications of the
theory of neural network to medicine. In particular suppose for a given disease D, belonging to the category of
immune deficiency diseases or cancers, there are numbers of drugs each with
partial remedial effect on D. We are
going to formulate a cocktail consisting of mixture of the above drugs with
optimal remedial effect on D.
Oct 19, 2015Open AccessArticle
Background: Human growth factors serve as secretomes that regulate skin
cell proliferation/differentiation and production of extracellular elements
of the matrix and treat photo-aging. Microneedling of skin can also improve
aging skin by facilitating normal wound healing of the temporary dermal conduits for therapeutic and cosmetic
benefits. Objectives: This open, randomized split-face and single-center
controlled study evaluated the safety and efficacy of the application of a
Apr 29, 2015Open AccessArticle
During the past decades, producing micro- and nano-particles of drugs is
gaining attention since it is possible to modify the solubility of insoluble
drugs in the gastronical fluids significantly. Respect to this fact, in the
current investigation, rapid expansion of supercritical carbon dioxide (RESS)
for fabricating the micro-particles of cetirizine is investigated. In this way,
different operational conditions including extraction pressure (160 - 220 bar),
extraction temperature (308 - 328 K)...
Jan 28, 2015Open AccessArticle
A typical medical Magnetic Resonance Imaging (MRI) contains a Local
transmit/receive coil. Magnetic coil design is very important in study of the
human brain and for neurological therapeutics technique. Precise spatial localization
of stimulation sites is the key of efficient functional magnetic stimulations.
Others have examined this issue at radio frequencies. This paper develops circular
coils, figure-of-8 coils and coil array elements in order to realize a
transcranial magnetic stimulator, a...
Jan 22, 2015Open AccessArticle
Background: Lack of
access to essential medicines is one of the most important public health
problems in Ethiopia. The objective of this study was to verify availability, affordability and prices of essential medicines in primary health care units and private medicine outlets of
South Wollo Zone. Methods:
A facility-based cross-sectional study was undertaken in 10 primary health care units and 10
private medicine outlets. Data were collected through patient exit interview,
record review, observa...
Dec 10, 2014Open AccessArticle
Currently, the model is based on the Clinical
Laboratory. It is a great centre that performs almost all of the techniques. Thanks to the automation of them. These
laboratories receive samples from centres that often are some kilometers away.
Time spent between collection and processing must be as short as possible and this is a requirement to
care about in order to process the samples in optimal conditions.
Transport logistic factor is essential to achieve the right balance between
Aug 28, 2014Open AccessArticle
Affective disorders are a group of psychiatric
diseases that can affect an individual at any given age. Also called mood
disorders, they can be distinguished into two different types: major depressive
disorder, also called major depression, and bipolar disorder, which is known as
manic depression. People affected by major depression most often have a low
mood, and are consistently in a state of unhappiness. Although it was shown
that genetics play a role in the predisposition of depression, this...
Jun 16, 2014Open AccessArticle
Background: At household levels drug may be hoarded and re-utilized inappropriately, shared within families and/or outside family and unnecessarily utilized in self-medication. Therefore this study was conducted to assess drug utilization at household level in Nekemte town and surrounding rural areas western Ethiopia. Methods: It was conducted on 844 households’ head through in-terviewing where households were stratified into urban and rural; a household was selected by using systematic random a...