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Mar 26, 2024Open    Access

Could X-Ray Irradiation Be Used as an “Irradiation Vaccine”?

Gao-De Li
In medical practice, X-ray is mainly used as a diagnostic test and a type of radiation therapy for cancer and other diseases. However, the X-rays seem no use in the prevention of diseases. Since X-rays can alter gene expression patterns in host cells, it might have capacity to protect people from all viral infections based on our antiviral theory. We assume that X-ray irradiation on the upper respiratory tract could protect normal people from respiratory viral infections. If a low-dose X-ray irr...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111337


Dec 08, 2023Open    Access

The Mechanism of Drug Resistance in Cellular Pathogens: A Hypothesis

Gao-De Li
Drug resistance in pathogens including cancer cells, bacteria, protozoa, fungi and viruses remains the major global health challenge. To deal with drug resistance in pathogens, an understanding of drug resistance development is of great importance. Recently, we published a hypothesis that drug resistance in malaria parasites could be determined by the altered 3D genome architecture which regulates many normal genes in malaria parasites to form a “specific antidrug group of protein combinations” ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110971


Nov 10, 2023Open    Access

Hemolysis Supported by Levofloxacin in an SS Sickle Cell Patient

Mamadou Cellou Balde, Mamadou Saliou Balde, Alpha Boubacar Bah, Mamadou Falilou Diallo, Ibrahim Cherif, Luciana Spataru, Zenab Awada, Laetitia Caumette, Marie Annick Cadeac, Bernard Delmas, Philippe Montane De La Roque, Joséphine Thomazeau, Algassimou Bah, Mamadou Sere Bah, Mohamed Lamine Kaba, Alpha Oumar Bah
The occurrence of acute hemolysis in a patient with stable hemoglobinosis can be of corpuscular or extra-corpuscular origin. We report the case of a patient with sickle cell disease SS stable for twenty years, who is treated with levofloxacin for sepsis with a urinary starting point. Biology: hyperleukocytosis at 33,570/mm3 made up of 90% neutrophils and CRP at 160 mg/l, hemolytic, mechanical, nonthrombocytic microcytic anemia (Hb at 8.3 g/dl, VGM at 70 μm3, haptoglobulin collapsed ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110193


Aug 30, 2023Open    Access

About the Method of Increasing the Effectiveness of Antibiotics Using Microwaves

Boris L. Ikhlov, Irene Evgenyevna Tregubova, Lev Samuilovith Ratkin
The formula for the natural frequency of torsional vibrations of the DNA helix is obtained by methods of mathematical physics. The data on the dependence of E. coli survival on the time of exposure to centimeter waves were analyzed, the numerical coefficient in the resulting formula was determined. According to this formula, the resonant frequency for the DNA of another strain of E. coli was found. When irradiated with centimeter waves of this frequency, a significant decrease in t...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110434


Aug 28, 2023Open    Access

Effectiveness of Botulinum Toxin A First Injection on Gastrocnemius Muscle Spasticity in Children with Cerebral Palsy: Clinical and Elastosonography Study

Soumaya Boudokhane, Amine Kalai, Houda Migaou, Ons Borgi, Badii Hmida, Anis Jellad, Zohra Ben Salah Frih
Background: An accurate assessment of the spasticity in the spastic forms of cerebral palsy (CP) is important to establish the effectiveness of therapeutic management. The modified Ashworth scale (MAS) is the most frequently used method in the assessment of spasticity in clinical practice. However, this method does not allow an objective, precise and reliable assessment because of the lack of standardization and the low level of reliability. Elastosonography (ES) is an imaging method that assess...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110517


Jul 31, 2023Open    Access

Contributions of Medicinal Plants in the Treatment of Oral Diseases

Jalila Dakkaki, Samir Ibenmoussa, Mustapha Sidqui
In dentistry, herbal medicine naturally falls within the professional capacity of stomatologists or dental surgeons and can be particularly useful. The use of medicinal plants, for preventive, therapeutic purposes or for oral hygiene, falls within the professional capacity of doctors-stomatologists and dental surgeons. But they have to be competent in the matter, especially since no plant is harmless. After regulatory information, for documentary purposes, some examples of use are reported and, ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1109935


Jun 13, 2023Open    Access

A New Strategy to Protect the Cell from Damage

Boris L. Ikhlov, Andrey V. Melnichenko
The article theoretically and experimentally substantiates a new method in the free-radical theory of aging, where the target is not the free radicals but the DNA molecules; while radioprotectors are used as antioxidants, previously used to protect the body from radiation damage. A brief overview of various strategies and methods in gerontology is provided. In the quasicrystalline model of DNA, the role of impurity levels is considered. The electronic spectra of DNA bases were calculated by the ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110147


May 24, 2023Open    Access

Vertigo and H4 Antagonist Effect on Vestibular Symptoms

Leena Saeed, Hanna Elbashir Mohamed Ali, Zeinab Abdalgadeer Ali Abdalla, Sarra Fadlalla Elabbas, Marwa Eltaj Eltayeb, Wafa Mukhtar Mohamed Mukhtar
Vertigo is a condition when a patient feels that the objects around him are moving, and this condition can lead to falls and serious incidences. Vertigo has various etiologies including central, peripheral, psychogenic, and medication-induced vertigo. The most common cause is benign paroxysmal positional vertigo (BPPV) then Meniere’s disease and labyrinthitis should be in the differential diagnosis. Ruling out serious conditions such as stroke is important. Various treatment options are used for...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110164


May 04, 2023Open    Access

An Ethnobotanical Study of Plants with Curative and Wound-Healing Properties in the Northern Zone of Cameroon

Christiane Pierrette Koungou, Ahmed Davy Ali, Djakaou Iya-Sou, Tchobsala, Helene Carole Edima
Wounds are skin lesions that manifest as an opening in the skin, and constitute a medical, social and economic problem for African populations. In particular, the relatively high cost of wound care makes the use of this treatment even more inaccessible to most, if not all, of the African population. The overall objective of the research is to determine the therapeutic effects that medicinal plants from the Northern zone of Cameroon may have on wound healing. The prospective study consisted of a ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1110026


Mar 29, 2023Open    Access

Microwave Induced Hormesis

Boris L. Ikhlov
The effect of centimeter waves of non-thermal level on four types of bacteria has been studied. On E. coli strains, a sharp increase in survival during the first cycle of cell division was obtained. The mechanism of inhibition of pathogenic bacteria by a weak electromagnetic field is explained. The mechanism of stimulating the survival of bacteria associated with the activation of genes that reduces the number of dying bacteria is explained. The general form of the modified Ferhulst equat...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1109835


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