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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

Avenanthramide-C prevents noise- and drug-induced hearing loss while protecting auditory hair cells from oxidative stress

DOI: 10.1038/s41420-019-0195-1

Keywords: Drug development, Cell death in the nervous system

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Abstract:

a Experimental timeline. AVN-C was provided intraperitoneally to the control models (without noise) and either (12 or 24) hours prior to exposure to a single noise trauma with 95?dB SPL. A week later, the auditory brainstem response (ABR) was evaluated using click and tone burst stimuli. b AVN-C effectively prevented transient hearing loss due to noise. n?=?3 per each group, *P?<?0.05, **P?<?0.01, ***P?<?0.00

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