%0 Journal Article
%T Avenanthramide-C prevents noise- and drug-induced hearing loss while protecting auditory hair cells from oxidative stress
%A Alphonse Umugire
%A Dami Kim
%A Hyong-Ho Cho
%A Hyung-Seok Kim
%A Munyoung Choi
%A Sungsu Lee
%J Archive of "Cell Death Discovery".
%D 2019
%R 10.1038/s41420-019-0195-1
%X a Experimental timeline. AVN-C was provided intraperitoneally to the control models (without noise) and either (12 or 24) hours prior to exposure to a single noise trauma with 95£¿dB SPL. A week later, the auditory brainstem response (ABR) was evaluated using click and tone burst stimuli. b AVN-C effectively prevented transient hearing loss due to noise. n£¿=£¿3 per each group, *P£¿<£¿0.05, **P£¿<£¿0.01, ***P£¿<£¿0.00
%K Drug development
%K Cell death in the nervous system
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614387/