Mesial temporal sclerosis in children

mesial temporal sclerosis is the most frequent cause of drug-resistant temporal lobe epilepsy but has a satisfactory response to surgery, and is considered infrequent in children. objective: to evaluate the clinical, electrographic and radiological spectrum of the disease in children. method: retrospective study by review of charts of 44 children with a diagnosis of mesial temporal sclerosis on magnetic resonance imaging, attended at the "hospital das clínicas" of the university of s？o paulo faculty of medicine. results: febrile seizure was identified in the history of 54% of the patients. injuries at the left side predominated in patients with schooling difficulties (p=0.049), in those with the first seizures between six months and five years (p=0.021) and in those with complex febrile seizure (p=0.032). thirteen patients were submitted to surgery and of these, eight remained without seizures. conclusion: febrile seizure may be related in a more direct way to the presence of left-side mesial temporal sclerosis.