Parameters of glycemic control and their relationship with zinc concentrations in blood and with superoxide dismutase enzyme activity in type 2 diabetes patients

objective: this study assessed the relationship between the parameters of glycemic control, and zinc concentrations in blood and superoxide dismutase enzyme activity in type 2 diabetes patients. subjects and methods: seventy-three individuals, aged between 25 and 59 years, were divided into the experimental group (type 2 diabetes patients, n = 36) and control group (n = 37). plasma and erythrocyte zinc concentrations, superoxide dismutase activity, and parameters of glycemic control were analyzed. results: mean plasma zinc concentration was 74.1 ± 10.7 μg/dl and 68.8 ± 9.6 μg/dl, erythrocyte zinc concentration was 48.1 ± 9.5 μg/ghb and 41.2 ± 8.0 μg/ghb, and superoxide dismutase activity was 2248.9 ± 300.0 u/ghb and 2059.6 ± 285.4 u/ghb, in the experimental group and the control group, respectively (p < 0.05). conclusion: type 2 diabetes patients showed a positive response to oxidative stress due to adequate zinc concentration in blood and increased activity of superoxide dismutase, and the enzyme was influenced by serum insulin.