%0 Journal Article
%T Parameters of glycemic control and their relationship with zinc concentrations in blood and with superoxide dismutase enzyme activity in type 2 diabetes patients
%A Lima
%A Vanessa Batista de Sousa
%A Sampaio
%A Fabiane de Ara¨²jo
%A Bezerra
%A Daila Leite Chaves
%A Moita Neto
%A Jos¨¦ Machado
%A Marreiro
%A Dilina do Nascimento
%J Arquivos Brasileiros de Endocrinologia & Metabologia
%D 2011
%I Sociedade Brasileira de Endocrinologia e Metabologia
%R 10.1590/S0004-27302011000900006
%X objective: this study assessed the relationship between the parameters of glycemic control, and zinc concentrations in blood and superoxide dismutase enzyme activity in type 2 diabetes patients. subjects and methods: seventy-three individuals, aged between 25 and 59 years, were divided into the experimental group (type 2 diabetes patients, n = 36) and control group (n = 37). plasma and erythrocyte zinc concentrations, superoxide dismutase activity, and parameters of glycemic control were analyzed. results: mean plasma zinc concentration was 74.1 ¡À 10.7 ¦Ìg/dl and 68.8 ¡À 9.6 ¦Ìg/dl, erythrocyte zinc concentration was 48.1 ¡À 9.5 ¦Ìg/ghb and 41.2 ¡À 8.0 ¦Ìg/ghb, and superoxide dismutase activity was 2248.9 ¡À 300.0 u/ghb and 2059.6 ¡À 285.4 u/ghb, in the experimental group and the control group, respectively (p < 0.05). conclusion: type 2 diabetes patients showed a positive response to oxidative stress due to adequate zinc concentration in blood and increased activity of superoxide dismutase, and the enzyme was influenced by serum insulin.
%K diabetes mellitus type 2
%K zinc
%K superoxide dismutase
%K chronic hyperglycemia.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-27302011000900006&lng=en&nrm=iso&tlng=en