Líquen plano hipertrófico disseminado: relevante resposta à acitretina

hyperthrofic lichen planus is considered a variant of lichen planus with marked epidermal hyperplasia in response to persistent itch. it is clinically, characterized by symmetric hyperkeratotic plaques, of purplish-grey color, often located in the pretibial region. intense pruritus, refractoriness to conventional treatments and the possibility of association of the long-term injuries with squamous cell carcinoma requires an effective treatment. the first-line treatment is corticosteroids which can be applied either topically or systemically. other therapeutic modalities proposed are: nb-uvb phototherapy or puva, immunosuppressive drugs and systemic retinoids, notably acitretin. we report a case with exuberant clinical presentation of hyperthrofic lichen planus with excellent response to acitretin after nine months of treatment