%0 Journal Article
%T L¨ªquen plano hipertr¨®fico disseminado: relevante resposta ¨¤ acitretina
%A Jaime
%A Thais Jerez
%A Jaime
%A Tatiana Jerez
%A Guaraldi
%A Bianca de Mello
%A Melo
%A Daniel Fernandes
%A Jeunon
%A Thiago
%A Lerer
%A Claudio
%J Anais Brasileiros de Dermatologia
%D 2011
%I Sociedade Brasileira de Dermatologia
%R 10.1590/S0365-05962011000700025
%X hyperthrofic lichen planus is considered a variant of lichen planus with marked epidermal hyperplasia in response to persistent itch. it is clinically, characterized by symmetric hyperkeratotic plaques, of purplish-grey color, often located in the pretibial region. intense pruritus, refractoriness to conventional treatments and the possibility of association of the long-term injuries with squamous cell carcinoma requires an effective treatment. the first-line treatment is corticosteroids which can be applied either topically or systemically. other therapeutic modalities proposed are: nb-uvb phototherapy or puva, immunosuppressive drugs and systemic retinoids, notably acitretin. we report a case with exuberant clinical presentation of hyperthrofic lichen planus with excellent response to acitretin after nine months of treatment
%K acitretin
%K immunosuppressive drugs
%K lichen planus
%K prednisone.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0365-05962011000700025&lng=en&nrm=iso&tlng=en