Caavuranamide, a novel steroidal alkaloid from the ripe fruits of Solanum caavurana Vell. (Solanaceae)

phytochemical investigation of the ripe fruits of solanum caavurana vell. (solanaceae) afforded a novel steroidal alkaloid with spirosolane-type skeleton, named as caavuranamide, together with the alkaloids 4-tomatiden-3-one and 5α-tomatidan-3-one. their structures were elucidated on the basis of spectroscopic methods. the antiproliferative and antimicrobial activities for the ethanolic extract, sub-fractions obtained from partition and acid-base treatment were also evaluated. caavuranamide showed antibacterial activity similar to the chloramphenicol positive control against rhodococcus equi.