%0 Journal Article
%T Caavuranamide, a novel steroidal alkaloid from the ripe fruits of Solanum caavurana Vell. (Solanaceae)
%A Vaz
%A Nelissa Pacheco
%A Costa
%A Emmanoel V.
%A Santos
%A ¨¦rica L.
%A Mikich
%A Sandra Bos
%A Marques
%A Francisco A.
%A Braga
%A Raquel M.
%A Delarmelina
%A Camila
%A Duarte
%A Marta C. T.
%A Ruiz
%A Ana L¨²cia T. G.
%A Souza
%A Vanessa H. S.
%A Carvalho
%A Jo£¿o E. de
%A Maia
%A Beatriz H. L. N. Sales
%J Journal of the Brazilian Chemical Society
%D 2012
%I Sociedade Brasileira de Qu¨ªmica, SBQ
%R 10.1590/S0103-50532012000200025
%X phytochemical investigation of the ripe fruits of solanum caavurana vell. (solanaceae) afforded a novel steroidal alkaloid with spirosolane-type skeleton, named as caavuranamide, together with the alkaloids 4-tomatiden-3-one and 5¦Á-tomatidan-3-one. their structures were elucidated on the basis of spectroscopic methods. the antiproliferative and antimicrobial activities for the ethanolic extract, sub-fractions obtained from partition and acid-base treatment were also evaluated. caavuranamide showed antibacterial activity similar to the chloramphenicol positive control against rhodococcus equi.
%K solanum caavurana
%K solanaceae
%K caavuranamide
%K steroidal alkaloids
%K spirosolane.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0103-50532012000200025&lng=en&nrm=iso&tlng=en