In vitro adherence of Candida albicans isolated from patients with chronic periodontitis

adherence is considered an extremely important virulence factor in yeast. objective: the aim of this study was to analyze the adherence to epithelial cells of c. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. material and methods: candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. suspensions of c. albicans (106 cells/ml) and epithelial cells (105 cells/ml) were mixed and incubated at 37oc for 1 h. the number of yeasts adhered to 25 epithelial cells was counted. results: the number of c. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (student's t-test, p=0.000). conclusion:the results of the present study suggest a higher candida adherence of samples isolated from patients with chronic periodontitis.