%0 Journal Article %T In vitro adherence of Candida albicans isolated from patients with chronic periodontitis %A Machado %A Adriana Gadotti %A Komiyama %A Edson Yukio %A Santos %A Silvana Sol¨¦o Ferreira dos %A Jorge %A Antonio Olavo Cardoso %A Brighenti %A Fernanda Louren£¿£¿o %A Koga-Ito %A Cristiane Yumi %J Journal of Applied Oral Science %D 2011 %I University of S?o Paulo %R 10.1590/S1678-77572011005000014 %X adherence is considered an extremely important virulence factor in yeast. objective: the aim of this study was to analyze the adherence to epithelial cells of c. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. material and methods: candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. suspensions of c. albicans (106 cells/ml) and epithelial cells (105 cells/ml) were mixed and incubated at 37oc for 1 h. the number of yeasts adhered to 25 epithelial cells was counted. results: the number of c. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (student's t-test, p=0.000). conclusion:the results of the present study suggest a higher candida adherence of samples isolated from patients with chronic periodontitis. %K candida albicans %K cell adhesion %K periodontitis %K virulence factors. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1678-77572011000400015&lng=en&nrm=iso&tlng=en