Anorectal melanoma is a rare tumor representing less than 1% of anorectal cancers and around 0.3% of malignant melanomas. Its prognosis is particularly poor due to the early occurrence of metastases. We report the case of a 65-year-old man presenting with rectorrhagia and anal pain, initially diagnosed as hemorrhoidal disease. Subsequent proctological examination revealed an ulcerating-bourging tumor, confirmed histologically as an anorectal melanoma. After a normal extension workup, an abdominoperineal amputation was performed. Anorectal melanoma is a pathology with a poor prognosis, requiring early diagnosis to improve chances of survival.
References
[1]
Jutten, E., Kruijff, S., Francken, A.B., Lutke Holzik, M.F., van Leeuwen, B.L., van Westreenen, H.L., etal. (2021) Surgical Treatment of Anorectal Melanoma: A Systematic Review and Meta-Analysis. BJSOpen, 5, zrab107. https://doi.org/10.1093/bjsopen/zrab107
[2]
Baniyaseen, K.A., Saeed, M., Albonni, A.O., Abdulshakour, B.M., Dairi, G., Al-Allaf, F.A., etal. (2019) Primary Anorectal Amelanotic Melanoma: The First Case Report from Saudi Arabia. MiddleEastJournalofDigestiveDiseases, 11, 166-173. https://doi.org/10.15171/mejdd.2019.144
[3]
Chang, A.E., Karnell, L.H. and Menck, H.R. (1998) The National Cancer Data Base Report on Cutaneous and Noncutaneous Melanoma: A Summary of 84,836 Cases from the Past Decade. Cancer, 83, 1664-1678. https://doi.org/10.1002/(sici)1097-0142(19981015)83:8<1664::aid-cncr23>3.0.co;2-g
[4]
Melhouf, M.M., El Amrani, N., Mathieu-Daude, H. and Dubois, J.B. (1995) Anorectal Malignant Melanomas: About 5 Cases and Review of the Literature. Annales de Gastroentérologie et d’Hépatologie, 31, 209-212.
[5]
Sielezneffi, I., Boutboul, R., Thomas, P., Henric, A. and Denis, O. (1993) Primary Anorectal Malignant Melanomas: 2 Cases. La Presse Médicale, 22, 1999-2001.
[6]
Haddad, F., Nadir, S., Benkhaldoun, L., Alaoui, R. and Cherkaoui, A. (2005) Mélanome anorectal primitif. LaPresseMédicale, 34, 85-88. https://doi.org/10.1016/s0755-4982(05)88233-8
[7]
Stefanou, A. and Nalamati, S.P.M. (2011) Anorectal Melanoma. ClinicsinColonandRectalSurgery, 24, 171-176. https://doi.org/10.1055/s-0031-1286001
[8]
Nam, S., Kim, C.W., Baek, S.J., Hur, H., Min, B.S., Baik, S.H., etal. (2014) The Clinical Features and Optimal Treatment of Anorectal Malignant Melanoma. AnnalsofSurgicalTreatmentandResearch, 87, 113-117. https://doi.org/10.4174/astr.2014.87.3.113
[9]
Chen, H., Cai, Y., Liu, Y., He, J., Hu, Y., Xiao, Q., etal. (2016) Incidence, Surgical Treatment, and Prognosis of Anorectal Melanoma from 1973 to 2011: A Population-Based SEER Analysis. Medicine, 95, e2770. https://doi.org/10.1097/md.0000000000002770
[10]
Latteri, S., Teodoro, M., Malaguarnera, M., Mannino, M., Currò, G. and La Greca, G. (2017) Abdominal Perineal Resection or Wilde Local Excision in Primary Anorectal Malignant Melanoma. Case Report and Review. AnnalsofMedicine&Surgery, 19, 74-77. https://doi.org/10.1016/j.amsu.2017.03.039
Hoang, C., Ferry, J., Le Charpentier, Y., Charbit, L., Gisselbrecht, C. and Dubost, C. (1981) Primary Rectal Malignant Melanoma: A Case Report and Review of the Literature. Gastroentérologie Clinique et Biologique, 5, 445-451.