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Vocational Education 2025
基于挑战性学习的药物分析综合实验设计
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Abstract:
针对高职院校药物分析综合实验教学中存在的问题，将挑战性学习和课程思政引入药物分析综合实验课程。以高效液相色谱法测定槐米中芦丁的含量，并进行方法学考察为挑战性学习任务，通过指导学生查阅资料、实验方案设计、实验方案实施、结果分析和开展课程思政，提升学生独立设计实验、自主解决问题、实践能力和职业素养，为高职院校培养高素质技术技能人才提供参考。
In view of present problems of practice teaching pharmaceutical analysis in higher vocational colleges, the challenge based learning method and ideological and political education were applied to the course of comprehensive experiment of pharmaceutical analysis. The contents of rutin in sophora japonica were determined by high performance liquid chromatography and methodological investigation was a challenging learning task. By guiding students to consult documents, design the experimental schemes, implement experimental schemes, analyze results, and carry out ideological and political education, students improved in designing experiments independently, solving problems independently, practicing ability, and achieving professional accomplishment. It provides a reference for higher vocational colleges to cultivate high-quality technical and technical talents.
| [1] | 徐洵. 现代高职教育实习实训基地协同建设研究[J]. 教育理论与实践, 2022, 42(33): 29-33. |
| [2] | 曹登华. 基于职业教育类型特点的实训教学改革[J]. 天津职业大学学报, 2023, 32(6): 71-75. |
| [3] | 韩薇, 耿翔, 李梅. 高职药物分析实训课程改革与实践[J]. 山西卫生健康职业学院学报, 2023, 33(5): 165-167. |
| [4] | 王慧玉, 张杰, 刘婷婷, 等. 混合式模式下药物分析实验课程渐进融入思政教学的探索[J]. 药学教育, 2023, 39(3): 38-42. |
| [5] | 林健. 面向“六卓越一拔尖”人才培养的挑战性学习[J]. 清华大学教育研究, 2020, 41(2): 45-57. |
| [6] | 金青, 何虹. 应用型地方高校课程挑战性学习模式设计与实践[J]. 中国职业技术教育, 2019(26): 33-40. |
| [7] | 孙宏斌, 冯婉玲, 马璟. 挑战性学习课程的提出与实践[J]. 中国大学教学, 2016(7): 26-31. |
| [8] | 杨伟, 唐璞, 骆无穷, 等. 基于工程类专业基础课的挑战性课程教学方法讨论[J]. 高教学刊, 2019(21): 86-88, 92. |
| [9] | Jung, C.H., Zhou, S., Ding, G.X., Kim, J.H., Hong, M.H., Shin, Y., et al. (2006) Antihyperglycemic Activity of Herb Extracts on Streptozotocin-Induced Diabetic Rats. Bioscience, Biotechnology, and Biochemistry, 70, 2556-2559. https://doi.org/10.1271/bbb.60238 |
| [10] | Wang, H., Lin, F., Wu, Y., Guo, W., Chen, X., Xiao, C., et al. (2023) Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury. ACS Nano, 17, 12176-12187. https://doi.org/10.1021/acsnano.3c00360 |
| [11] | Zhao, T., He, F., Zhao, K., Yuxia, L., Li, H., Liu, X., et al. (2023) A Triple-Targeted Rutin-Based Self-Assembled Delivery Vector for Treating Ischemic Stroke by Vascular Normalization and Anti-Inflammation via ACE2/Ang1-7 Signaling. ACS Central Science, 9, 1180-1199. https://doi.org/10.1021/acscentsci.3c00377 |
| [12] | Elberry, A., Mufti, S., Al-Maghrabi, J., Ghareib, S., Mosli, H., El-Halawany, A., et al. (2020) The Protective Effect of Sophora Japonica on Prostatic Hypertrophy and Inflammation in Rat. Inflammopharmacology, 28, 1525-1536. https://doi.org/10.1007/s10787-020-00723-5 |
| [13] | Rashid, H., Rasool, S., Ali, Y., Khan, K. and Martines, M.A.U. (2020) Anti-Cancer Potential of Sophoridine and Its Derivatives: Recent Progress and Future Perspectives. Bioorganic Chemistry, 99, Article 103863. https://doi.org/10.1016/j.bioorg.2020.103863 |
| [14] | 中国药典委员会. 中国药典[M]. 北京: 中国医药科技出版社, 2020. |
| [15] | 张朝阳, 马明, 李金霖, 等. 以丙酮为溶剂提取纯化槐米中芦丁的工艺研究[J]. 化学研究, 2024, 35(1): 29-39. |
| [16] | 周旭, 陈红. 槐米中芦丁的提取及应用研究[J]. 山东化工, 2023, 52(19): 64-66. |
