|
|
Nursing Science 2024
多感官刺激在阿尔茨海默病应用现状的范围综述
|
Abstract:
目的：对多感官刺激在阿尔茨海默病中的应用现状进行范围综述，为临床试验提供参考。方法：计算机检索Cochrane Library、PubMed、Web of science、EMbase、中国知网、万方、维普网等数据库，检索时限为建库至2024年04月12日，对纳入文献进行汇总与分析。结果：共计纳入10篇文献，当前多感官刺激已被应用于阿尔茨海默病的各个阶段；常用的干预方法包括固定主题干预和个性化干预；干预频率均为2次/周，每次干预时间30~50 min，干预周期4~16周不等；结局指标包含认知功能、精神行为症状、心理状态、日常生活能力。结论：多感官刺激在阿尔茨海默病中应用效果良好，但缺乏规范化干预范式与评价工具，其长期效果不明确，仍需在未来深入探索，建立长期随访队列，开展相关高质量研究。
Objective: To provide a scoping review of the current status of multisensory stimulation in Alzheimer’s disease for clinical trials. Methods: Computer searches were performed on Cochrane Library, PubMed, Web of science, EMbase, China Knowledge, Wanfang, and Wipo databases, with a time frame from the establishment of the library to 12 April 2024, and the included literature was summarized and analyzed. Results: A total of 10 papers were included, and multisensory stimulation has been applied to various stages of Alzheimer’s disease; commonly used intervention methods include fixed-topic interventions and personalized interventions; the frequency of interventions is 2 times/week, the duration of each intervention is 30-50 min, and the intervention period is from 4 to 16 weeks; the outcome indicators include cognitive function, psycho-behavioral symptoms, mental status, and daily life ability. Conclusion: Multi-sensory stimulation has been used effectively in Alzheimer’s disease, but the lack of standardized intervention paradigms and evaluation tools makes its long-term effects unclear, and it still needs to be explored in depth in the future, to establish a long-term follow-up cohort and to carry out relevant high-quality studies.
| [1] | Ren, R., Qi, J., Lin, S., Liu, X., Yin, P., Wang, Z., et al. (2022) The China Alzheimer Report 2022. General Psychiatry, 35, e100751. https://doi.org/10.1136/gpsych-2022-100751 |
| [2] | 张占军, 姜淼, 张俊英, 等. 社区老年脑健康体检与痴呆风险筛查体系构建与实践——北京方案[J]. 科学通报, 2020, 65(14): 1339-1347. |
| [3] | Ren, Y., Zhou, D., Xing, Q., Gong, F. and Tang, W. (2022) Economic Evaluation of the Screening for Alzheimer’s Disease in China. Frontiers in Aging Neuroscience, 14, Article ID: 968842. https://doi.org/10.3389/fnagi.2022.968842 |
| [4] | 王晓成. 阿尔茨海默病疾病负担研究[D]: [硕士学位论文]. 太原: 山西医科大学, 2012. |
| [5] | Lindenberger, U. and Baltes, P.B. (1994) Sensory Functioning and Intelligence in Old Age: A Strong Connection. Psychology and Aging, 9, 339-355. https://doi.org/10.1037/0882-7974.9.3.339 |
| [6] | Pinto, J.O., Dores, A.R., Geraldo, A., Peixoto, B. and Barbosa, F. (2020) Sensory Stimulation Programs in Dementia: A Systematic Review of Methods and Effectiveness. Expert Review of Neurotherapeutics, 20, 1229-1247. https://doi.org/10.1080/14737175.2020.1825942 |
| [7] | 周瑶, 楼妍, 胡紫燕, 等. 多感官刺激对痴呆病人干预效果的Meta分析[J]. 循证护理, 2021, 7(3): 307-314. |
| [8] | 陈晓, 赵翠, 吕中月, 等. 非侵入性多感官刺激治疗在阿尔茨海默病认知功能治疗中的应用进展[J]. 阿尔茨海默病及相关病杂志, 2024, 7(1): 77-81. |
| [9] | 刘维, 詹秀玲, 刘宏, 等. 多感官刺激疗法对老年阿尔茨海默病患者激越行为和认知功能的影响[J]. 医学综述, 2023(9): 1848-1852. |
| [10] | 谌彪, 赵静波, 沈艳, 等. 多感官刺激疗法对阿尔茨海默病患者精神行为和心理状态的改善分析[J]. 心理月刊, 2022, 17(18): 44-46. |
| [11] | 周淑玲, 师新娟, 张绡琦. 多感官刺激疗法对阿尔茨海默病患者精神行为和心理状态的影响[J]. 医学综述, 2021, 27(5): 1022-1026. |
| [12] | 毛艳. 多感官刺激对老年期痴呆患者精神行为症状、认知功能及生活质量的影响分析[J]. 中国医学前沿杂志(电子版), 2018, 10(2): 97-101. |
| [13] | Sánchez, A., Maseda, A., Marante-Moar, M.P., de Labra, C., Lorenzo-López, L. and Millán-Calenti, J.C. (2016) Comparing the Effects of Multisensory Stimulation and Individualized Music Sessions on Elderly People with Severe Dementia: A Randomized Controlled Trial. Journal of Alzheimer’s Disease, 52, 303-315. https://doi.org/10.3233/jad-151150 |
| [14] | Sánchez, A., Marante-Moar, M.P., Sarabia, C., de Labra, C., Lorenzo, T., Maseda, A., et al. (2015) Multisensory Stimulation as an Intervention Strategy for Elderly Patients with Severe Dementia: A Pilot Randomized Controlled Trial. American Journal of Alzheimer’s Disease & Other Dementias？, 31, 341-350. https://doi.org/10.1177/1533317515618801 |
| [15] | Wang, Y.Y., Chiu, C.H., Chen, Y.Y., et al. (2011) The Efficacy of Multi-Sensory Environment Therapy on Psychological, Behavioral Symptoms among Elderly Patients with Dementia. The Journal of Nursing, 58, 48-58. |
| [16] | Staal, J.A., Amanda, S., Matheis, R., Collier, L., Calia, T., Hanif, H., et al. (2007) The Effects of Snoezelen (Multi-Sensory Behavior Therapy) and Psychiatric Care on Agitation, Apathy, and Activities of Daily Living in Dementia Patients on a Short Term Geriatric Psychiatric Inpatient Unit. The International Journal of Psychiatry in Medicine, 37, 357-370. https://doi.org/10.2190/pm.37.4.a |
| [17] | Baker, R., Holloway, J., Holtkamp, C.C.M., Larsson, A., Hartman, L.C., Pearce, R., et al. (2003) Effects of Multi‐Sensory Stimulation for People with Dementia. Journal of Advanced Nursing, 43, 465-477. https://doi.org/10.1046/j.1365-2648.2003.02744.x |
| [18] | Baker, R., Bell, S., Baker, E., Holloway, J., Pearce, R., Dowling, Z., et al. (2001) A Randomized Controlled Trial of the Effects of Multi‐Sensory Stimulation (MSS) for People with Dementia. British Journal of Clinical Psychology, 40, 81-96. https://doi.org/10.1348/014466501163508 |
| [19] | 田金洲, 解恒革, 王鲁宁, 等. 中国阿尔茨海默病痴呆诊疗指南(2020年版) [J]. 中华老年医学杂志, 2021, 40(3): 269-283. |
| [20] | Collier, L. and Jakob, A. (2016) The Multisensory Environment (MSE) in Dementia Care: Examining Its Role and Quality from a User Perspective. HERD: Health Environments Research & Design Journal, 10, 39-51. https://doi.org/10.1177/1937586716683508 |
| [21] | Yesantharao, L., Cai, Y., Schrack, J.A., Gross, A.L., Wang, H., Bilgel, M., et al. (2023) Sensory Impairment and Beta‐Amyloid Deposition in the Baltimore Longitudinal Study of Aging. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 15, e12407. https://doi.org/10.1002/dad2.12407 |
| [22] | Martorell, A.J., Paulson, A.L., Suk, H., Abdurrob, F., Drummond, G.T., Guan, W., et al. (2019) Multi-Sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition. Cell, 177, 256-271.e22. https://doi.org/10.1016/j.cell.2019.02.014 |
| [23] | Devanand, D.P., Lee, S., Manly, J., Andrews, H., Schupf, N., Doty, R.L., et al. (2015) Olfactory Deficits Predict Cognitive Decline and Alzheimer Dementia in an Urban Community. Neurology, 84, 182-189. https://doi.org/10.1212/wnl.0000000000001132 |
| [24] | Curhan, S.G., Willett, W.C., Grodstein, F. and Curhan, G.C. (2019) Longitudinal Study of Hearing Loss and Subjective Cognitive Function Decline in Men. Alzheimer’s & Dementia, 15, 525-533. https://doi.org/10.1016/j.jalz.2018.11.004 |
| [25] | Palta, P., Chen, H., Deal, J.A., Sharrett, A.R., Gross, A., Knopman, D., et al. (2018) Olfactory Function and Neurocognitive Outcomes in Old Age: The Atherosclerosis Risk in Communities Neurocognitive Study. Alzheimer’s & Dementia, 14, 1015-1021. https://doi.org/10.1016/j.jalz.2018.02.019 |
| [26] | Murphy, C. (2018) Olfactory and Other Sensory Impairments in Alzheimer Disease. Nature Reviews Neurology, 15, 11-24. https://doi.org/10.1038/s41582-018-0097-5 |
| [27] | 宣传司. 国家卫生健康委员会2021年4月8日例行新闻发布会文字实录[EB/OL]. http://www.nhc.gov.cn/xcs/s3574/202104/0c1cf92f2b7b4cfe890234a1c3d5593f.shtml, 2024-04-13. |
| [28] | Jakob, A. and Collier, L. (2017) Sensory Enrichment for People Living with Dementia: Increasing the Benefits of Multisensory Environments in Dementia Care through Design. Design for Health, 1, 115-133. https://doi.org/10.1080/24735132.2017.1296274 |
