%0 Journal Article
%T 多感官刺激在阿尔茨海默病应用现状的范围综述<br>A Review of the Current Scope of Multisensory Stimulation for Use in Alzheimer’s Disease
%A 柏亚妹
%A 马云云
%A 石佳瑞
%A 宋玉磊
%A 张薛晴
%A 徐桂华
%J Nursing Science
%P 763-769
%@ 2168-5614
%D 2024
%I Hans Publishing
%R 10.12677/ns.2024.136109
%X 目的：对多感官刺激在阿尔茨海默病中的应用现状进行范围综述，为临床试验提供参考。方法：计算机检索Cochrane Library、PubMed、Web of science、EMbase、中国知网、万方、维普网等数据库，检索时限为建库至2024年04月12日，对纳入文献进行汇总与分析。结果：共计纳入10篇文献，当前多感官刺激已被应用于阿尔茨海默病的各个阶段；常用的干预方法包括固定主题干预和个性化干预；干预频率均为2次/周，每次干预时间30~50 min，干预周期4~16周不等；结局指标包含认知功能、精神行为症状、心理状态、日常生活能力。结论：多感官刺激在阿尔茨海默病中应用效果良好，但缺乏规范化干预范式与评价工具，其长期效果不明确，仍需在未来深入探索，建立长期随访队列，开展相关高质量研究。<br />
Objective: To provide a scoping review of the current status of multisensory stimulation in Alzheimer’s disease for clinical trials. Methods: Computer searches were performed on Cochrane Library, PubMed, Web of science, EMbase, China Knowledge, Wanfang, and Wipo databases, with a time frame from the establishment of the library to 12 April 2024, and the included literature was summarized and analyzed. Results: A total of 10 papers were included, and multisensory stimulation has been applied to various stages of Alzheimer’s disease; commonly used intervention methods include fixed-topic interventions and personalized interventions; the frequency of interventions is 2 times/week, the duration of each intervention is 30-50 min, and the intervention period is from 4 to 16 weeks; the outcome indicators include cognitive function, psycho-behavioral symptoms, mental status, and daily life ability. Conclusion: Multi-sensory stimulation has been used effectively in Alzheimer’s disease, but the lack of standardized intervention paradigms and evaluation tools makes its long-term effects unclear, and it still needs to be explored in depth in the future, to establish a long-term follow-up cohort and to carry out relevant high-quality studies.
%K 多感官刺激，阿尔茨海默病，范围综述<br>Multisensory Stimulation
%K Alzheimer’s Disease
%K Scope Review
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=90258