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金纳米颗粒在病毒性疾病中的应用进展
Progress in the Application of Gold Nanoparticles in Viral Diseases

DOI: 10.12677/NAT.2024.141001, PP. 1-11

Keywords: 金纳米颗粒,病毒,病毒性疾病,检测,治疗
Gold Nanoparticles
, Virus, Viral Disease, Detection, Treatment

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Abstract:

灵敏特异的检测方案和有效的抗病毒疗法对于预防治疗病毒感染至关重要。金纳米颗粒(Gold Nanoparticles, AuNPs)是指尺寸在1~100 nm的金属纳米材料,因其良好的生物相容性、较低的生物毒性和可调节的尺寸而广受关注,目前常应用于生物分子传感、药物递送、疫苗制备、癌症治疗和抗菌药物等领域。正是由于AuNPs的这些特性,使其在预防和治疗已知或潜在未知的病毒感染等方面也具有独特的优势。本文简要介绍了AuNPs在对抗病毒性疾病中发挥的作用,主要涵盖了病毒检测、疫苗制备、药物递送和抗病毒治疗四个方面的研究进展,并探讨了AuNPs在应用开发中面临的挑战以及未来的发展前景。
Sensitive and specific detection protocols and effective antiviral therapy are essential for the prevention and treatment of viral infections. Gold nanoparticles (AuNPs), metallic nanomaterials with dimensions ranging from 1 to 100 nanometers, are highly regarded for their excellent biocompatibility, low biotoxicity, and adjustable size properties. Currently, AuNPs are extensively utilized in various fields such as biomolecular sensing, drug delivery, vaccine development, cancer treatment, and antimicrobial drugs. Notably, the unique characteristics of AuNPs offer significant potential in preventing and treating viral infections, including both known and potential unknown viruses. This article primarily focuses on the role of AuNPs in combating viral diseases, covering recent research advancements in areas such as viral detection, vaccine preparation, drug delivery, and antiviral treatment. It also explores the challenges faced in the practical application and development of AuNPs, as well as their future prospects.

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