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长链非编码RNA RUNX1-IT1在恶性肿瘤中的研究进展
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Abstract:
长链非编码RNA在调节基因表达水平上发挥重要的作用，广泛参与人类疾病的进展。LncRNA RUNX1-IT1被发现在多种疾病中处于失调状态，如肝细胞癌、结直肠癌、肺癌及子宫内膜癌等。本综述总结近些年LncRNA RUNX1-IT1相关研究，试图揭示其在疾病中的进展机制，为进一步研究提供参考。
Long non-coding RNAs (lncRNAs) play a pivotal role in the modulation of gene expression levels, exerting a profound influence on the progression of human diseases. LncRNA RUNX1-IT1 has been observed to be dysregulated in various pathological conditions, including hepatocellular carcinoma, colorectal cancer, lung cancer, and endometrial carcinoma, among others. This comprehensive re-view aims to synthesize recent research pertaining to LncRNA RUNX1-IT1, endeavoring to elucidate its mechanistic contributions to disease progression, thus offering valuable insights for future in-vestigations.
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