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结合珠蛋白与2型糖尿病肾病的临床研究概况
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Abstract:
糖尿病是一种以糖代谢紊乱为主要临床特点的代谢疾病，糖尿病肾脏病是指由糖尿病所致的慢性肾脏病，是糖尿病最常见的慢性并发症之一，现已成为慢性肾脏病和终末期肾病的主要原因。本文旨在进一步研究早期反映糖尿病肾病的指标，使糖尿病肾病患者更早得到诊断、治疗。
Diabetes is a metabolic disease with the main clinical characteristics of glucose metabolism disor-der. Diabetes nephropathy refers to the chronic kidney disease caused by diabetes, which is one of the most common chronic complications of diabetes, and has become the main cause of chronic kidney disease and end-stage kidney disease. This article aims to further study the indicators re-flecting diabetes nephropathy in the early stage, so that patients with diabetes nephropathy can be diagnosed and treated earlier.
| [1] | Global Report on Diabetes. WHO Website. http://www.who.int |
| [2] | 中国2型糖尿病防治指南(2017年版) [J]. 中国实用内科杂志, 2018, 38(4): 292-344. |
| [3] | Li, Y., Teng, D., Shi, X., et al. (2020) Prevalence of Diabetes Recorded in Mainland China Using 2018 Diagnostic Criteria from the American Diabetes Association: National Cross Sectional Study. BMJ, 369, m997.
https://doi.org/10.1136/bmj.m997 |
| [4] | Cheng, H.T., Xu, X., Lim, P.S., et al. (2021) Worldwide Epidemiology of Diabetes-Related End-Stage Renal Disease, 2000-2015. Diabetes Care, 44, 89-97. https://doi.org/10.2337/dc20-1913 |
| [5] | Afkarian, M., Zelnick, L.R., Hall, Y.N., et al. (2016) Clinical Manifesta-tions of Kidney Disease among US Adults with Diabetes, 1988-2014. JAMA, 316, 602-610. https://doi.org/10.1001/jama.2016.10924 |
| [6] | de Boer, I.H., Rue, T.C., Hall, Y.N., et al. (2011) Temporal Trends in the Prevalence of Diabetic Kidney Disease in the United States. JAMA, 305, 2532-2539. https://doi.org/10.1001/jama.2011.861 |
| [7] | Zhang, X.X., Kong, J. and Yun, K. (2020) Prevalence of Diabetic Nephropathy among Patients with Type 2 Diabetes Mellitus in China: A Meta-Analysis of Observational Studies. Jour-nal of Diabetes Research, 2020, Article ID: 2315607. https://doi.org/10.1155/2020/2315607 |
| [8] | Anders, H.J., Huber, T.B., Isermann, B., et al. (2018) CKD in Diabetes: Diabetic Kidney Disease versus Nondiabetic Kidney Disease. Nature Reviews Nephrology, 14, 361-377. https://doi.org/10.1038/s41581-018-0001-y |
| [9] | Zhang, L., Long, J., Jiang, W., et al. (2016) Trends in Chronic Kidney Disease in China. The New England Journal of Medicine, 375, 905-906. https://doi.org/10.1056/NEJMc1602469 |
| [10] | American Diabetes Association (2020) Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes-2020. Diabetes Care, 43, S135-S151. https://doi.org/10.2337/dc20-S011 |
| [11] | Vallon, V. and Thomson, S.C. (2020) The Tubular Hypothesis of Nephron Filtration and Diabetic Kidney Disease. Nature Reviews Nephrology, 16, 317-336. https://doi.org/10.1038/s41581-020-0256-y |
| [12] | Tervaert, T.W., Mooyaart, A.L., Amann, K., et al. (2010) Patho-logic Classification of Diabetic Nephropathy. Journal of the American Society of Nephrology, 21, 556-563. https://doi.org/10.1681/ASN.2010010010 |
| [13] | Mise, K., Hoshino, J., Ueno, T., et al. (2016) Prognostic Value of Tubulointerstitial Lesions, Urinary N-Acetyl-β- d-glucosaminidase, and Urinary β2-Microglobulin in Patients with Type 2 Diabetes and Biopsy-Proven Diabetic Nephropathy. Clinical Journal of the American Society of Nephrology, 11, 593-601.
https://doi.org/10.2215/CJN.04980515 |
| [14] | Hoshino, J., Furuichi, K., Yamanouchi, M., et al. (2018) A New Pathological Scoring System by the Japanese Classification to Predict Renal Outcome in Diabetic Nephropathy. PLOS ONE, 13, e0190923.
https://doi.org/10.1371/journal.pone.0190923 |
| [15] | Adler, A.I., Stevens, R.J., Manley, S.E., et al. (2003) Develop-ment and Progression of Nephropathy in Type 2 Diabetes: The United Kingdom Prospective Diabetes Study (UKPDS64). Kidney International, 63, 225-232.
https://doi.org/10.1046/j.1523-1755.2003.00712.x |
| [16] | Wu, B., Zhang, S., Lin, H., et al. (2018) Prevention of Re-nal Failure in Chinese Patients with Newly Diagnosed Type 2 Diabetes: A Cost-Effectiveness Analysis. Journal of Dia-betes Investigation, 9, 152-161.
https://doi.org/10.1111/jdi.12653 |
| [17] | 韩志明, 谷欣. 血清结合珠蛋白对2型糖尿病患者肾功能预测价值分析[J]. 检验医学与临床, 2015(17): 2605-2607. |
| [18] | Andersen, C., Stodkilde, K., Saederup, K.L., et al. (2017) Haptoglo-bin. Antioxidants & Redox Signaling, 26, 814-831.
https://doi.org/10.1089/ars.2016.6793 |
| [19] | Conway, B., Fried, L. and Orchard, T. (2008) Hemoglobin and Overt Nephropathy Complications in Type 1 Diabetes. Annals of Epidemiology, 18, 147-155. https://doi.org/10.1016/j.annepidem.2007.07.110 |
| [20] | Goldenstein, H., Levy, N.S., Lipener, Y.T., et al. (2012) Haptoglobin Genotype and Its Role in Determining Heme-Iron Mediated Vascular Disease. Pharmacological Research, 66, 1-6. https://doi.org/10.1016/j.phrs.2012.02.011 |
| [21] | Dahan, I., Thauho, N., Nakhoul, F., Nakhoul, N., Jabaly, H. and Farber, E. (2016) Haptoglobin Polymorphism as an Independent Predictor of Diabetic Nephropathy and Reti-nopathy. Harefuah, 155, 439-442. |
| [22] | Orchard, T.J., Sun, W., Cleary, P.A., et al. (2013) Haptoglobin Genotype and the Rate of Renal Function Decline in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Nterven-tions and Complications Study. Diabetes, 62, 3218-3223. https://doi.org/10.2337/db13-0256 |
| [23] | Orchard, T.J., Backlund, J.C., Costacou, T., et al. (2016) Haptoglobin 2-2 Genotype and the Risk of Coronary Artery Disease in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC). Journal of Diabetes and Its Complications, 30, 1577-1584.
https://doi.org/10.1016/j.jdiacomp.2016.07.014 |
| [24] | Nakhoul, F., Nakhoul, N., Asleh, R., Miller-Lotan, R. and Levy, A.P. (2013) Is the Hp 2-2 Diabetic Mouse Model a Good Model to Study Diabetic Nephropathy? Diabetes Re-search and Clinical Practice, 100, 289-297.
https://doi.org/10.1016/j.diabres.2013.02.004 |
| [25] | 李宏杰, 要瑞莉, 武慧丽, 等. 触珠蛋白在家兔肠系膜上动脉闭塞性休克前后血清差异表达的研究[J]. 中国应用生理学杂志, 2012, 28(2): 143-144, 178. |
| [26] | 王美娟, 侯俊秀. 尿结合珠蛋白肌酐比对糖尿病肾病的临床研究[J]. 内蒙古医科大学学报, 2018, 40(4): 344-348+357. https://doi.org/10.16343/j.cnki.issn.2095-512x.2018.04.006 |
| [27] | Bhensdadia, N.M., Hunt, K.J., Lopes-Virella, M.F., et al. (2013) Urine Haptoglobin Levels Predict Early Renal Functional Decline in Patients with Type 2 Diabetes. Kidney International, 83, 1136-1143.
https://doi.org/10.1038/ki.2013.57 |
