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局灶性皮层发育不良的研究进展
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Abstract:
局灶性皮层发育不良(focal cortical dysplasia, FCD)是耐药性癫痫最常见的病因，其根本病理改变是大脑皮层发育畸形，临床表现为幼儿时期发作的局灶性癫痫。FCD的早期诊断及治疗，能有效减轻患者神经发育障碍的症状。通过总结近年来在FCD认识方面的进展，并对其分型、发病机制、诊断及治疗方面的研究进展加以综述，以期为今后的实验研究及临床诊疗提供参考。
Focal cortical dysplasia is the most common cause of drug-resistant epilepsy. Its fundamental pathological change is cerebral cortical malformation, which is clinically manifested as focal epilep-sy in childhood. Early diagnosis and treatment of FCD can effectively alleviate the symptoms of neu-rodevelopmental disorders to summarize the progress in understanding FCD in recent years, and review the research progress in classification, pathogenesis, diagnosis and treatment of FCD, with a view to providing reference for future experimental research and clinical diagnosis and treatment.
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