Background: Infertility is well-known global health problem
that has significant impacts on an individual, families and communities. Many modifiable lifestyle risk
factors increase the risk of women to several reproductive disorders. Aim:
This study established the relationship between obesity and Hypothalamic-Pituitary-Ovarian (HPO) axis
hormones in infertile women in the Niger Delta Region, Nigeria. Methodology:
Six hundred and twenty-six (626) women aged
18-40years comprising of 513 obese infertile women and 113 non obese women who served as control were recruited for
the study. Anthropometric measurements were taken and Body Mass Index was
calculated. A non-fasting venous blood sample was collected from the women and
analyzed for serum Estrogen, Luteinizing Hormone (LH), Follicle Stimulating
Hormone (FSH), Progesterone, Inhibin B, and Prolactin using Enzyme linked immunosorbent
assay method. Results
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