%0 Journal Article
%T Association of Body Mass Index with Hypothalamus-Pituitary-Ovarian Axis Hormones in Infertile Women in the Niger Delta Region, Nigeria
%A Onitsha Enebrayi Nelson
%A Ezeiruaku Ferdinand Chukwuma
%J Open Journal of Obstetrics and Gynecology
%P 671-685
%@ 2160-8806
%D 2022
%I Scientific Research Publishing
%R 10.4236/ojog.2022.128060
%X <strong>Background</strong><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><strong>:</strong> Infertility is well-known global health problem
that has significant impacts </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">on</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\"> an individual, families and communities. Many modifiable lifestyle risk
factors increase the risk of women to several reproductive disorders. </span><b><span style=\"font-family:Verdana;\">Aim</span></b><span style=\"font-family:Verdana;\">:
This study established the relationship between obesity </span></span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">and Hypothalamic-Pituitary-Ovarian (HPO) axis
hormones in infertil</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">e women in the Niger Delta Region, Nigeria. </span><b><span style=\"font-family:Verdana;\">Methodology</span></b><span style=\"font-family:Verdana;\">:
Six hundred and twen</span><span style=\"font-family:Verdana;\">ty-six (626) women aged
18</span></span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">-</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">40</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">years comprising of 513 obese infertil</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">e women and 113 non obese women who served as control were recruited for
the study. Anthropometric measurements were taken and Body Mass Index was
calculated. A non-fasting venous blood sample was collected from the women and
analyzed for serum Estrogen, Luteinizing Hormone (LH), Follicle Stimulating
Hormone (FSH), Progesterone, Inhibin B, and Prolactin using Enzyme linked immunosorbent
assay method. </span><b><span style=\"font-family:Verdana;\">Results</span></b><span
%K Body Mass Index
%K Hypothalamus-Pituitary Ovarian Axis
%K Infertility
%K Obesity and Female Reproductive Hormones
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=118997