|
|
- 2019
Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor SmoothenedDOI: https://doi.org/10.1016/j.str.2018.11.003 Abstract: ？ MD simulations predict a cholesterol binding site on the SMO transmembrane domain ？ This site is distinct from those observed for class A GPCRs ？ Potential of mean force calculations reveal the selectivity of sterol binding ？ SMO forms strong encounter complexes with PIP2 lipid
|
