%0 Journal Article
%T Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened
%J -
%D 2019
%R https://doi.org/10.1016/j.str.2018.11.003
%X £¿ MD simulations predict a cholesterol binding site on the SMO transmembrane domain £¿ This site is distinct from those observed for class A GPCRs £¿ Potential of mean force calculations reveal the selectivity of sterol binding £¿ SMO forms strong encounter complexes with PIP2 lipid
%U https://www.cell.com/structure/fulltext/S0969-2126(18)30422-2