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- 2019
Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and BiomechanicsDOI: https://doi.org/10.1016/j.stem.2019.02.009 Abstract: ？ Normal HSCs are stiffer and less deformable than mature blood cells ？ Ptpn21 loss decreases cell stiffness and increases mobility/deformability in HSCs ？ Deletion of Ptpn21 results in HSC egress due to impaired retention in the niche ？ Ptpn21 modulates cellular mechanics by dephosphorylation of Septin1 (Tyr 246
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