%0 Journal Article
%T Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics
%J -
%D 2019
%R https://doi.org/10.1016/j.stem.2019.02.009
%X £¿ Normal HSCs are stiffer and less deformable than mature blood cells £¿ Ptpn21 loss decreases cell stiffness and increases mobility/deformability in HSCs £¿ Deletion of Ptpn21 results in HSC egress due to impaired retention in the niche £¿ Ptpn21 modulates cellular mechanics by dephosphorylation of Septin1 (Tyr 246
%U https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(19)30051-7