|
|
- 2019
Whole-Organ Genomic Characterization of Mucosal Field Effects Initiating Bladder CarcinogenesisDOI: https://doi.org/10.1016/j.celrep.2019.01.095 Abstract: ？ Field change in DNA methylation is the initiator of bladder carcinogenesis ？ The methylation changes suppressed immunity and dysregulated Ras-related pathways ？ Founder ACIN1 mutation in normal mucosa clonally expanded in progression to carcinoma ？ Cells with mutations of 22 genes expanded clonally with progression to carcinom
|
