%0 Journal Article
%T Whole-Organ Genomic Characterization of Mucosal Field Effects Initiating Bladder Carcinogenesis
%J -
%D 2019
%R https://doi.org/10.1016/j.celrep.2019.01.095
%X £¿ Field change in DNA methylation is the initiator of bladder carcinogenesis £¿ The methylation changes suppressed immunity and dysregulated Ras-related pathways £¿ Founder ACIN1 mutation in normal mucosa clonally expanded in progression to carcinoma £¿ Cells with mutations of 22 genes expanded clonally with progression to carcinom
%U https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30132-9