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- 2019
Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson’s Disease ModelsDOI: https://doi.org/10.1016/j.neuron.2018.12.004 Abstract: ？ Thalamic neurons more potently activated indirect pathway striatal neurons in PD mice ？ This amplification was dependent upon striatal cholinergic interneurons (ChIs) ？ ChI-activated, presynaptic nicotinic receptors increased thalamic glutamate release ？ Suppressing this signaling pathway restored motor learning in PD mic
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