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- 2019
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained ImmunityDOI: https://doi.org/10.1016/j.cmet.2018.09.003 Abstract: ？ Itaconate is a central component of the inhibitory effects during immune tolerance ？ β-Glucan counteracts the tolerizing effects of LPS by inhibiting IRG1 expression ？ β-Glucan restores the expression of SDH in tolerant monocytes ？ β-Glucan-induced trained immunity has the potential to revert immunoparalysi
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