%0 Journal Article
%T The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
%J -
%D 2019
%R https://doi.org/10.1016/j.cmet.2018.09.003
%X £¿ Itaconate is a central component of the inhibitory effects during immune tolerance £¿ ¦Â-Glucan counteracts the tolerizing effects of LPS by inhibiting IRG1 expression £¿ ¦Â-Glucan restores the expression of SDH in tolerant monocytes £¿ ¦Â-Glucan-induced trained immunity has the potential to revert immunoparalysi
%U https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30568-0