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-  2019 

甲状腺未分化癌88例治疗及预后分析

DOI: 10.3971/j.issn.1000-8578.2019.18.1639

Keywords: A Retrospective Study,Oncolytic Adenovirus RCA-TERT-Ad35 Carrying Human Telomerase Reverse Transcriptase Promoter Targets Breast Cancer Stem Cells,Influence of GSTP-1 Genetic Variation on Prognosis of Postoperative Glioblastoma Patients Received Temozolomide Combined with Radiotherapy Regimens,Clinicopathologic Characteristics and Prognosis of De Novo Metastatic Breast Cancer Patients,Prognostic and Clinicopathological Significance of PD-L1 Expression for Colorectal Cancer: A Meta-analysis,Research Progress of Intestinal Microbiota and Immune Checkpoint Inhibitors,Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer,A Comprehensive Review of Androgen Deprivation Therapy and Immunotherapy on Prostate Cancer,Diffusion-weighted Magnetic Resonance Imaging Evaluates Salivary Gland Function Damage in Nasopharyngeal Carcinoma Patients Treated with Intensity-modulated Radiation Therapy,Value of 18F-FDG PET/CT in Evaluating Chemotherapeutic Effect of Diffuse Large B Cell Lymphoma Patients with Different CD5 Expression

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Abstract:

摘要 目的 探讨甲状腺未分化癌患者的生存状况及预后因素。方法 回顾性分析天津市肿瘤医院2003年1月—2016年5月收治的88例甲状腺未分化癌患者的临床及随访资料,采用Kaplan-Meier法及Cox多因素回归分析预后因素。结果 88例甲状腺未分化癌患者的中位生存时间为3.5月;6月生存率30.7%,1年生存率为22.7%,2年生存率为11.4%。单因素分析显示,肿物最大径、年龄、远处转移、淋巴结转移、分期、白细胞数、放疗、化疗、甲状腺结节、不同手术方式、综合治疗是影响甲状腺未分化癌患者预后的因素。多因素分析显示,影响预后的独立因素为年龄、分期、白细胞数、综合治疗。结论 甲状腺未分化癌预后极差,对于ⅣA、ⅣB期患者手术切除联合术后放化疗的综合治疗方案可延长其生存期,即使丧失手术机会的患者仍能从放疗和(或)化疗中获益

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