%0 Journal Article
%T 甲状腺未分化癌88例治疗及预后分析
%A 刘敬敬
%A 曹水
%J 肿瘤防治研究
%D 2019
%R 10.3971/j.issn.1000-8578.2019.18.1639
%X 摘要 目的 探讨甲状腺未分化癌患者的生存状况及预后因素。方法 回顾性分析天津市肿瘤医院2003年1月—2016年5月收治的88例甲状腺未分化癌患者的临床及随访资料，采用Kaplan-Meier法及Cox多因素回归分析预后因素。结果 88例甲状腺未分化癌患者的中位生存时间为3.5月；6月生存率30.7%，1年生存率为22.7%，2年生存率为11.4%。单因素分析显示，肿物最大径、年龄、远处转移、淋巴结转移、分期、白细胞数、放疗、化疗、甲状腺结节、不同手术方式、综合治疗是影响甲状腺未分化癌患者预后的因素。多因素分析显示，影响预后的独立因素为年龄、分期、白细胞数、综合治疗。结论 甲状腺未分化癌预后极差，对于ⅣA、ⅣB期患者手术切除联合术后放化疗的综合治疗方案可延长其生存期，即使丧失手术机会的患者仍能从放疗和（或）化疗中获益
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%U http://www.zlfzyj.com/CN/abstract/abstract9395.shtml