Magnesium stearate, a widely-used food additive, exhibits a lack of in vitro and in vivo genotoxic potential

DOI: 10.1016/j.toxrep.2017.10.003

Keywords: 2AA, 2-aminoanthracene, 9AA, 9-aminoacridine hydrochloride monohydrate, ADI, acceptable daily intake, AF-2, 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, DMSO, dimethyl sulfoxide, EFSA, European Food Safety Authority, FAO, Food and Agriculture Organization of the United Nations, ENNG, N-ethyl-N'-nitro-N-nitrosoguanidine, FDA, U.S. Food and Drug Administration, GLP, Good Laboratory Practice, JECFA, Joint FAO/WHO Expert Committee on Food Additives, MMC, mitomycin C, MN, micronucleus or micronuclei, MN-PCE, micronucleated polychromatic erythrocyte(s), OECD, Organization for Economic Cooperation and Development, PCE, polychromatic erythrocyte(s), WHO, World Health Organization Genotoxicity, Food additive, Magnesium stearate, DNA damage, Dietary supplement, Joint FAO/WHO Expert Committee on Food Additives (JECFA)

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