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-  2017 

Association of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients

DOI: 10.2147/PGPM.S131390

Keywords: kidney transplantation, polymorphism, PPP3CA, tacrolimus, adverse events, Brazilian patients

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Abstract:

The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate the influence of the PPP3CA c.249G>A variant on the clinical outcomes of kidney transplant recipients

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