%0 Journal Article %T Association of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients %A Claudia R Felipe %A Fabiana DV Genvigir %A Helio Tedesco-Silva %A Jr %A Jose O Medina-Pestana %A Mario H Hirata %A Patricia C Salgado %A Rosario DC Hirata %A Sonia Q Doi %J Archive of "Pharmacogenomics and Personalized Medicine". %D 2017 %R 10.2147/PGPM.S131390 %X The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate the influence of the PPP3CA c.249G>A variant on the clinical outcomes of kidney transplant recipients %K kidney transplantation %K polymorphism %K PPP3CA %K tacrolimus %K adverse events %K Brazilian patients %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386607/