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-  2016 

First oncolytic virus approved for melanoma immunotherapy

DOI: 10.1080/2162402X.2015.1115641

Keywords: Granulocyte macrophage colony-stimulating factor, Imlygic?, OncoVEXGM-CSF, OPTiM, talimogene laherparepvec, T-vec

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Abstract:

On 2015, October 27th, the US Food and Drug Administration (FDA) has officially approved talimogene laherparepvec (T-VEC, also known as OncoVEXGM-CSF) for use in melanoma patients with injectable but non-resectable lesions in the skin and lymph nodes. T-VEC (which is commercialized by Amgen, Inc. under the name of Imlygic?) becomes therefore the first oncolytic virus approved for cancer therapy in the US

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