%0 Journal Article %T First oncolytic virus approved for melanoma immunotherapy %A Guido Kroemer %A Jonathan Pol %A Lorenzo Galluzzi %J Archive of "Oncoimmunology". %D 2016 %R 10.1080/2162402X.2015.1115641 %X On 2015, October 27th, the US Food and Drug Administration (FDA) has officially approved talimogene laherparepvec (T-VEC, also known as OncoVEXGM-CSF) for use in melanoma patients with injectable but non-resectable lesions in the skin and lymph nodes. T-VEC (which is commercialized by Amgen, Inc. under the name of Imlygic£¿) becomes therefore the first oncolytic virus approved for cancer therapy in the US %K Granulocyte macrophage colony-stimulating factor %K Imlygic£¿ %K OncoVEXGM-CSF %K OPTiM %K talimogene laherparepvec %K T-vec %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760283/