Long noncoding RNA AK126698 inhibits proliferation and migration of non-small cell lung cancer cells by targeting Frizzled-8 and suppressing Wnt/β-catenin signaling pathway

Recent studies indicate that long noncoding RNAs (lncRNAs) play a key role in the control of cellular processes such as proliferation, metastasis, and differentiation. The lncRNA dysregulation has been identified in all types of cancer. We previously found that lncRNA {"type":"entrez-nucleotide","attrs":{"text":"AK126698","term_id":"34533276","term_text":"AK126698"}}AK126698 suppresses cisplatin resistance in A549 cells through the Wnt/β-catenin signaling pathway. However, the clinical significance of lncRNA {"type":"entrez-nucleotide","attrs":{"text":"AK126698","term_id":"34533276","term_text":"AK126698"}}AK126698 and the molecular mechanisms through which it regulates cancer cell proliferation and migration are largely unknown