%0 Journal Article
%T Long noncoding RNA AK126698 inhibits proliferation and migration of non-small cell lung cancer cells by targeting Frizzled-8 and suppressing Wnt/¦Â-catenin signaling pathway
%A Bin Hu
%A Chunxiao Liu
%A Hui Li
%A Tong Li
%A Xiao Fu
%A Yang Wang
%J Archive of "OncoTargets and therapy".
%D 2016
%R 10.2147/OTT.S100633
%X Recent studies indicate that long noncoding RNAs (lncRNAs) play a key role in the control of cellular processes such as proliferation, metastasis, and differentiation. The lncRNA dysregulation has been identified in all types of cancer. We previously found that lncRNA {"type":"entrez-nucleotide","attrs":{"text":"AK126698","term_id":"34533276","term_text":"AK126698"}}AK126698 suppresses cisplatin resistance in A549 cells through the Wnt/¦Â-catenin signaling pathway. However, the clinical significance of lncRNA {"type":"entrez-nucleotide","attrs":{"text":"AK126698","term_id":"34533276","term_text":"AK126698"}}AK126698 and the molecular mechanisms through which it regulates cancer cell proliferation and migration are largely unknown
%K long noncoding RNAs
%K Frizzled-8
%K NSCLC
%K Wnt/¦Â-catenin
%K proliferation
%K migration
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928661/