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-  2017 

Human Induced Pluripotent Stem Cells and the Modelling of Alzheimer’s Disease: The Human Brain Outside the Dish

DOI: 10.2174/1874205X01711010027

Keywords: Alzheimer’s Disease, Induced Pluripotent Stem Cells, AD Modelling, Human-mouse chimeric model, Microglia, Neuronal grafts, Neuroinflammation

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Abstract:

Neurodegenerative diseases like Alzheimer’s Disease (AD) are a global health issue primarily in the elderly. Although AD has been investigated using primary cultures, animal models and post-mortem human brain tissues, there are currently no effective treatments

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