%0 Journal Article
%T Human Induced Pluripotent Stem Cells and the Modelling of Alzheimer¡¯s Disease: The Human Brain Outside the Dish
%A Godwin Tong
%A Pablo Izquierdo
%A Rana Arham Raashid
%J Archive of "The Open Neurology Journal".
%D 2017
%R 10.2174/1874205X01711010027
%X Neurodegenerative diseases like Alzheimer¡¯s Disease (AD) are a global health issue primarily in the elderly. Although AD has been investigated using primary cultures, animal models and post-mortem human brain tissues, there are currently no effective treatments
%K Alzheimer¡¯s Disease
%K Induced Pluripotent Stem Cells
%K AD Modelling
%K Human-mouse chimeric model
%K Microglia
%K Neuronal grafts
%K Neuroinflammation
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678240/