Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment

The expression of IL-8 in mono-cultured and co-cultured osteosarcoma and normal cells. a Relative expression of IL-8 mRNA in hMSC and MG63. b Relative expression of IL-8 mRNA in MRC 5 and MG63. c Changes in gene expression in hMSCs after the co-culture with MG63. d Changes in gene expression in MG63 after the co-culture with hMSC